Eicke Latz Selected Research

Hereditary Sensory and Autonomic Neuropathies (HSAN)

1/2021	1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation.
1/2017	Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction.

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Eicke Latz Research Topics

Disease

66	Inflammation (Inflammations) 03/2024 - 08/2006
28	Infections 12/2023 - 12/2008
19	Atherosclerosis 01/2024 - 04/2010
13	Alzheimer Disease (Alzheimer's Disease) 03/2024 - 08/2008
12	Autoimmune Diseases (Autoimmune Disease) 11/2023 - 02/2005
9	Fibrosis (Cirrhosis) 01/2023 - 11/2015
8	Neurodegenerative Diseases (Neurodegenerative Disease) 10/2021 - 01/2013
7	Atherosclerotic Plaque (Atheroma) 01/2022 - 03/2013
6	Bites and Stings (Sting) 12/2023 - 11/2010
6	Virus Diseases (Viral Diseases) 01/2023 - 05/2003
6	Pneumonia (Pneumonitis) 02/2022 - 01/2010
6	Disease Progression 01/2022 - 01/2010
6	Neoplasms (Cancer) 01/2022 - 01/2017
5	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/2024 - 02/2005
5	COVID-19 11/2023 - 01/2020
5	Type 2 Diabetes Mellitus (MODY) 01/2021 - 05/2011
5	Neuroinflammatory Diseases 01/2021 - 01/2013
5	Rupture 01/2019 - 01/2013
4	Cognitive Dysfunction 03/2024 - 01/2013
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2024 - 03/2013
4	Obesity 10/2017 - 05/2011
4	Metabolic Diseases (Metabolic Disease) 09/2015 - 08/2011
3	Dementia (Dementias) 03/2024 - 01/2019
3	Colitis 01/2023 - 09/2010
3	Silicosis 02/2022 - 08/2008
3	Hypertension (High Blood Pressure) 11/2021 - 01/2017
3	Melanoma (Melanoma, Malignant) 01/2019 - 03/2009
3	Fever (Fevers) 03/2010 - 09/2003
2	Aortic Valve Stenosis (Aortic Stenosis) 01/2024 - 12/2022
2	Endotoxemia 11/2023 - 08/2006
2	Skin Diseases (Skin Disease) 11/2022 - 07/2021
2	Lung Injury 02/2022 - 01/2021
2	Parkinson Disease (Parkinson's Disease) 10/2021 - 01/2020
2	Contact Dermatitis (Eczema, Contact) 07/2021 - 01/2018
2	Hyperglycemia 01/2021 - 05/2011
2	Hereditary Sensory and Autonomic Neuropathies (HSAN) 01/2021 - 01/2017
2	Non-alcoholic Fatty Liver Disease 01/2021 - 09/2015
2	Tauopathies 01/2021 - 11/2019
2	Acute Lung Injury 01/2021 - 02/2015
2	Dysbiosis 01/2021 - 12/2015
2	Ileus 02/2020 - 01/2019

Drug/Important Bio-Agent (IBA)

65	InflammasomesIBA 03/2024 - 08/2008
27	CytokinesIBA 03/2024 - 04/2003
26	Proteins (Proteins, Gene)FDA Link 03/2024 - 02/2005
18	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 02/2005
15	CholesterolIBA 01/2024 - 04/2010
9	Amyloid (Amyloid Fibrils)IBA 01/2020 - 01/2013
8	Biomarkers (Surrogate Marker)IBA 01/2024 - 01/2018
8	Interleukin-18 (Interleukin 18)IBA 02/2022 - 04/2010
7	RNA (Ribonucleic Acid)IBA 01/2021 - 10/2006
6	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2016 - 12/2005
5	NLR ProteinsIBA 01/2024 - 08/2011
5	Interleukin-1 (Interleukin 1)IBA 01/2022 - 04/2010
5	Complement System Proteins (Complement)IBA 01/2022 - 03/2014
5	N- (1,2,3,5,6,7- hexahydro- S- indacen- 4- ylcarbamoyl)- 4- (2- hydroxy- 2- propanyl)- 2- furansulfonamideIBA 01/2021 - 03/2015
5	InterleukinsIBA 10/2020 - 04/2010
5	Peptides (Polypeptides)IBA 01/2018 - 08/2008
4	Nucleic AcidsIBA 01/2024 - 01/2016
4	Phosphotransferases (Kinase)IBA 12/2023 - 03/2011
4	LigandsIBA 12/2023 - 08/2013
4	ChemokinesIBA 11/2023 - 02/2005
4	VaccinesIBA 05/2023 - 04/2016
4	Interferon Type IIBA 01/2023 - 01/2016
4	LipidsIBA 12/2021 - 03/2013
4	InterferonsIBA 01/2021 - 04/2012
4	Toll-Like Receptor 9IBA 04/2010 - 02/2005
3	PyrinIBA 11/2022 - 03/2009
3	Silicon Dioxide (Silica)FDA LinkGeneric 02/2022 - 08/2008
3	Apolipoproteins E (ApoE)IBA 01/2022 - 01/2016
3	SaltsIBA 11/2021 - 01/2017
3	Desoxycorticosterone Acetate (DOCA)FDA Link 11/2021 - 01/2017
3	NucleotidesIBA 01/2021 - 11/2015
3	Pyrin Domain-Containing 3 Protein NLR FamilyIBA 10/2020 - 02/2015
3	Amyloid beta-PeptidesIBA 11/2019 - 08/2008
3	Nucleotide AptamersIBA 01/2019 - 01/2018
3	Antiviral Agents (Antivirals)IBA 11/2017 - 04/2012
3	AutoantibodiesIBA 12/2012 - 02/2005
2	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 12/2023 - 01/2021
2	Interleukin-6 (Interleukin 6)IBA 12/2023 - 01/2019
2	cyclic guanosine monophosphate-adenosine monophosphateIBA 12/2023 - 01/2021
2	Adenosine Monophosphate (AMP)IBA 12/2023 - 12/2015
2	ATP Citrate (pro-S)-Lyase (Citrate Synthase, ATP)IBA 12/2023 - 12/2021
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2023 - 09/2010
2	Dextrans (Dextran)FDA Link 01/2023 - 09/2010
2	Tetracycline (Achromycin)FDA LinkGeneric 02/2022 - 01/2021
2	AntibodiesIBA 01/2022 - 04/2012
2	Desoxycorticosterone (Deoxycorticosterone)IBA 11/2021 - 01/2017
2	Acetates (Acetic Acid Esters)FDA Link 11/2021 - 01/2017
2	Irritants (Vesicants)IBA 07/2021 - 01/2010
2	SphingolipidsIBA 01/2021 - 01/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 11/2015
2	DNA receptor (receptor, DNA)IBA 01/2021 - 04/2012
2	Leucine (L-Leucine)FDA Link 01/2021 - 01/2018
2	CollagenIBA 01/2019 - 01/2017
2	Liposomes (Liposome)IBA 01/2019 - 01/2018
2	Bacterial DNAIBA 01/2019 - 03/2011
2	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2018 - 10/2016

Therapy/Procedure

15	Therapeutics 03/2024 - 04/2003
2	Transcatheter Aortic Valve Replacement 01/2024 - 12/2022
2	Immunotherapy 11/2019 - 06/2018